I found that the program defaults to metric and only changes to English if the DXF file contains the [imath]INSUNITS[/imath] parameter. It does not seem to save any change back to the DXF.
One can manually add [imath]INSUNITS[/imath] to the DXF file and it selects the correct units.
I would like to see a feature that changes the default units in dxf2gcode when the units are not specified and possibly also a feature to save that option back to the DXF file. (That could present some other issues.)
In the meantime, I am trying to add BOSS5 support for my ancient Bridgeport mill. I have made some progress, but life keeps intervening and my python skills are weak at best!